I apologise in advance if any spoilers creep in to my ramblings. I'm going to do my darned best to avoid them, but no guarantees. You have been forewarned!
So, in order from ten to one, here are the best and brightest vessels in the 'Verse.
10: Battlestar Pegasus (BS-62)
She's big, she's bad, she's nicknamed "The Beast". She's Battlestar Pegasus, the latest, shiniest addition to the Colonial Fleet's arsenal prior to the Fall of the Twelve Colonies. Commanded by the ruthless Rear Admiral Helena Cain, this Mercury-class battlestar survived the Cylon assault on the Scorpion Fleet Shipyards, then went on to royally piss the Cylons off with hit-and-run attacks before she encountered Battlestar Galactica and the remains of humanity.
9: USS Defiant (NX-74205)
In the tough nugget, bad-ass starship category, USS Defiant is Starfleet's niftiest contribution. Compared to other starships, she may not be the biggest, but with pulse phasers and quantum torpedoes, not to mention a Romulan cloaking device, she's one of the meanest ships in Starfleet. And under the command of Captain Benjamin Sisko, she went around beating the living crap out of Cardassians and Jem'Hadar alike during the Dominion War.
8: USS Daedalus (BC-304)
Slipping in at 8 is the United States Air Force and its beautiful, kick-ass battlecruiser, USS Daedalus. Commanded by Colonel Steven Caldwell (played by X-Files alumni Mitch Pileggi - I won't deny the squee of happiness when I first saw him on Daedalus's bridge), this beast first saw action during the Wraith Siege of Atlantis. Since then, she's been outfitted with Asgard beam weapons and has generally gone tearing around the Pegasus Galaxy, beating the living crap out of any ships dumb enough to oppose the USAF's shiniest battlecruiser. Also joined by sister ships USS Odyssey, USS Apollo and USS George Hammond.
7: Super Star Destroyer Executor
When she first appears in Empire Strikes Back, you know some serious shit is going down. Darth Vader's flagship is probably the meanest entry in the Imperial Navy's arsenal after the timely demise of the Death Star. Easily as big as the Death Star itself (albeit flattened out), Executor spells doom to any Rebels as soon as it jumps into a star system. Well, at least it did until a poxy little A-Wing crashed into the bridge and took the whole thing out at the Battle of Endor. Up until then...she was a pretty bad-ass ship. Oh well. It was only because Darth Vader wasn't breathing heavily over everyone's shoulders and Force-choking dumb-ass admirals.
6: USS Enterprise (NCC-1701)
Specifically the NCC-1701 from the new movie. Although the original ship from the Original Series was beautiful, JJ Abrams injects new life into James T. Kirk's famous first command. Combine its gorgeous "ample nacelles" (thanks, Scotty) with her awesome crew and you have a pretty bad-ass ship. Best choice for Federation flagship by far...
5: USS Enterprise (NCC-1701-E)
...until you consider this beauty. While Kirk's Enterprise is a wonderful ship, she will never be as beautiful as Enterprise-E or have a captain as amazing and classically trained as the one and only Jean-Luc Picard. While his more famous command was Enterprise-D, it's Enterprise-E that steals the show here. And with the aforementioned captain at the helm, she beats out both Defiant and the "original" Enterprise as best ship in Starfleet. But does she really clinch the title? Let's see...
4: SSV Normandy (SR-1)
Coming in at 4 is Mass Effect's SSV Normandy, a nifty little ship, product of a collaboration between the Systems Alliance and the Turian Hierarchy. Equipped with an experimental drive core and stealth systems to make every other race in the galaxy weep, the flagship of humanity's first Spectre is a cheeky little number that anyone should be proud to command. And when piloted by Seth frakking Green...what more could you ask for?
3: USS Prometheus (NX-59650)
Alas, Enterprise-E, in spite of its Shakespeare-trained captain, failed to clinch the honour of Starfleet's best and brightest. That honour falls to USS Prometheus, featured only once (well, in focus), during the Star Trek: Voyager episode "Message in a Bottle". So what sets Prometheus apart from Defiant, Enterprise and Enterprise-E? Easy. Multi-vector assault mode. Built specifically for combat in the Dominion War, Prometheus is capable of splitting into three separate, fully-armed, warp-capable sections. Three-in-one starship? Now that's frakking bad-ass!
2: Battlestar Galactica (BS-75)
When it comes to bad-ass, though, no ship in any universe whatsoever beats this beauty. Star of the eponymous show, Battlestar Galactica is one of the toughest, most sublimely beautiful warships in existence. Over its long, long career, it's been nuked, tangled with numerous Cylon basestars and never fails to come out swinging. Under the faithful command of William Adama, it's no wonder humanity survived the Fall of the Twelve Colonies when they had this motherfrakker showing those frakking Toasters who's boss!
1: Serenity (03-K64)
Here she is. By far, indisputably, the most beautiful ship in the 'Verse. I won't lie. I want one. I want to live on it. She may not have weapons, but she's a ship you can love. Makes her home :) And she's so small, you could probably fit in her Galactica's flight pods, which means I could have both my favourite starships together. I could go on and on about why I love this ship, but just watch Firefly, watch Serenity, then you shall understand the true awesomeness of this humble cargo ship.
So there you have it. My (personal) top ten favourite starships. Feel free to scream at me for missing off ships you love, or to praise my selection. I hope you've all enjoyed this, as I hope to make more top tens. Proposed topics - sci-fi ladies and favourite starfighters. Until then, this has been my top ten favourite starships :D